
G1 Version
Optimus Prime is the leader of the Autobots, and the main protagonist of Transformers franchise. He is a wise, selfless figurehead who always aims to make peace with other non-hostile species, and leads the war against Decepticons and his archnemesis Megatron. His main transformation is a convoy, and he's armed with an ion blaster. The G1 version of Optimus Prime appears in Worst Hero And Villain War Ever, while the Transformers Animated version is set to appear in Heroes vs Villains, His version of Transformers Prime was confirmed to appear in Worst Heroes and Villains War Ever: The Sandbox.

Animated version
Contents
- 1 Heroes Vs Villains War-Part Two
- 2 Worst Heroes and Villains War Ever
- 3 Worst Heroes and Villains War Ever: The Sandbox
- 4 Villains War (Legion of Darkness)
- 5 Transformers vs Disney and Non Disney Villains War
- 6 CGI & Non-Disney Heroes vs. CGI, Disney, & Non-Disney Villains War
- 7 CGI & Non-Disney Heroes vs. CGI, Disney, & Non-Disney Villains War - Part Two
Heroes Vs Villains War-Part Two
Worst Heroes and Villains War Ever
Worst Heroes and Villains War Ever: The Sandbox
Villains War (Legion of Darkness)

Killed
As a reward for killing Jango Fett and for his royalty, Skeletor helped Megatron to kill his rival Optimus Prime.
Transformers vs Disney and Non Disney Villains War
Prepared for war
The Autobots of many Variations lead by a version of their leader Optimus Prime prepare to defeat the vatiations of the Decepticons and other Villains.