Moses is the main protagonist of the Dreamworks' animated movie The Prince of Egypt. Based on the actual Biblical prophet of God, Moses was born from the enslaved mother, Yocheved, along with his siblings, Aaron and Miriam, and lived formely in the luxury of the Egyptian empire, ruled by Pharaoh Seti and his consort, Queen Tuya, alongside with his step-brother, Rameses. He began to live a new life outside of the Land of Egypt after a tragic incident, as well as realising his true identity, eventually marrying Tzipporah, who took her in as a companion, and meeting God for the first time. When he learned, through God that the Hebrews must be liberated from Egypt, Moses travelled to Egypt and demanded the release of the Hebrews for the purpose to guide them to the "Promised Land". After many incidents, Rameses let the Hebrews lived their own life, though he later regretted his decision and unleashed his army on Moses and his people before meeting his own end after witnessing the power and wrath of God" After Rameses' defeat, Moses and the Hebrews continued unpertubed their journey to the "Promised Land".
Regarding the villain wars, Moses appeared in the first Heroes vs. Villains War, as one of the main commanders of the hero forces, mainly encouraging the heroes in their darkest moments, and guiding them to safety, providing them moral support. Over the course of the series, Moses was tasked in preventing Chernabog's rise into the universe with the help of his newfound allies, eventually banishing the arch-demon, when he was awakened on Bald Mountain, back to Hell, through the will of God. Since then, he bidded farewell to the heroes and departed with his people to the unknown, ending his role in the series.