Moses is the main protagonist of the Dreamworks' animated movie The Prince of Egypt. Based on the eponymous biblical prophet of God, Moses was born in the Egyptian empire, ruled by Pharaoh Seti I, from the enslaved mother Yocheved, along with his siblings Aaron and Miriam, before he was subsequently adopted by Seti' consort Queen Tuya to avoid Seti's massacre of the Istraelite infants; consequently, he lived alongside with Rameses, his step-brother and next-in-line of the Egyptian throne. He began to live a new life outside of the land of Egypt after killing an Egyptian worker, as well as realising his true identity, eventually marrying Tzipporah, who took her in as a companion, and meeting God for the first time. When he was tasked to free the Istraelites from Pharaoh Rameses as part of God's plan, Moses traveled to Egypt and demanded the release of his people for the purpose to guide them to the "Promised Land". After many incidents, Rameses let the Istraelites lived their own life, although he regretted his decision; thus, he unleashed his army on Moses and his people before meeting his own end, after witnessing the power and wrath of God. After Rameses' defeat, Moses and the Istraelites continued unpertubed their journey to the "Promised Land".
Regarding the villain wars, Moses appeared in the first Heroes vs. Villains War as one of the main commanders of the hero forces, mainly encouraging the heroes in their darkest moments, and guiding them to safety, providing them moral support. Over the course of the series, Moses was tasked in preventing Chernabog's rise into the universe with the help of his newfound allies, eventually banishing the arch-demon, when he was awakened on Bald Mountain, back to Hell through the will of God. Since then, he bidded farewell to the heroes and departed with his people to the unknown, ending his role in the series.