Dr. Greed's remote control is the device primarly used by Dr. Greed, originally appearing from the animated film The Fearless Four. When activated, it opens an abyss world beneath his factory. It is usually functioned whenever Dr. Greed disposes off his enemies or useless minions of his. By the climax of the original film, the Fearless Four's members claim the remote control, sending Dr. Greed, his henchmen, and his pet-snake to their doom. The remote control also appears in the villain tournaments whenever Dr. Greed is involved in any kind of conflict.
In the events of Heroes vs. Villains, the remote control retains the same role as it was in the original film with extra details on the continuity of the tournament. Particularly, Dr. Greed uses his remote control to battle the heroes like Francis' dogs and cats' faction, or to dispose any incapable and useless follower of the Animal Cruelty Squad like Aunt Sarah. In the wake of Dr. Greed's defeat in the battle of Dr. Greed's mansion, the Fearless Four's members claim the remote control, plummeting Dr. Greed, his henchmen, and his pet-snake to an abyss world beneath Dr. Greed's mansion.