Leah Estrogen

Leah Estrogen is the secondary protagonist of the animated segment of the movie, Osmosis Jones. A former secretary of the selfish ruler, Mayor Phlegmming, and the love-interest of the titular character of the movie, Leah, along with Osmosis Jones, currently rule over the human host of the live-action character, Frank Detorre.

According to the villains war context, Leah Estrogen is an alien being, rather than a virus itself, assuming fully personality. Though she appears briefly in the Non-Disney Villains Tournament, she marks her fully appearance and role in Heroes vs. Villains War.