Itachi Uchiha

Itachi Uchiha is Sasuke's brother and a major villain in Naruto.

Dio's Empire
Resurrected by Dio, Itachi hopes to make Naruto and the Nine-Tails Dio's slaves. He would then intend to challenge his brothers, Sasuke and Shisui to a fight to the death. During his quest for Dio, he entraps Maid Marian in a nightmarish coma via the Tsukuyomi where she would be in an infinite death loop such as being hanged, shot to death, etc.